| Research related to discovering the causes of | | | | Some researchers suspect virus or bacterial infection |
| rheumatoid arthritis has been unsuccessful in | | | | in the synovium could cause the immune response to |
| determining specific factors related to the disease. It | | | | body tissue. However, no specific infectious agent has |
| appears to be a combination of genetic risk factors | | | | been discovered as a possible cause of rheumatoid |
| combined with the environment. Rheumatoid arthritis | | | | arthritis. It has been established that tobacco use |
| differs from osteoarthritis or the wearing of joint tissue. | | | | increases the risk of developing rheumatoid arthritis. |
| The body develops a sense of immunity to normal | | | | Heredity and gender also play important roles in |
| body tissue and attacks as though it were a foreign | | | | increasing the risk factor. Women have a 70 percent |
| invader. | | | | increased risk compared to men. Genetics are not |
| The disease typically starts with an immune response | | | | suspected as a direct cause of rheumatoid arthritis. |
| to the thin layer of tissue that provides protective lining | | | | However, genetic conditions are believed to play a role |
| of the joints called the synovium. Lymphocytes, a | | | | in making an individual more susceptible to |
| particular type of cell in the immune system, releases a | | | | environmental conditions that do lead to the disease. |
| messenger, called cytokines that cause inflammation in | | | | Individuals experiencing joint pain could be developing |
| the joints. It is a progressive disease that continues to | | | | symptoms of the condition and should consult a |
| deteriorate as the individual becomes older. The | | | | physician. Early treatment helps slow the progression |
| disease eventually leads to further inflammation, pain | | | | of the disease. Regular exercise will strengthen |
| and eventual loss of joint function. Eventually, the | | | | muscles in joint regions to help reduce the pain and |
| disease attacks other joint related tissues such as | | | | discomfort associated with rheumatoid arthritis. |
| cartilage, tendons and ligaments. | | | | |