Snake Venom May Stop Arthritis Pain

The next time you see a snake, don’t kill it or drivescorpion stings that is used in many hospitals.
it away. That slithering serpent may save you fromThe idea that snake venom might be useful in treating
the pain of arthritis.arthritis occurred to Primor in the early 80s when
This bizarre revelation comes from Dr. Naftali Primor,Shulov told him that Russian immigrants used a healing
research and development manager for Shulovsalve supposedly made of viper venom to treat body
Institute for Sciences Ltd (SIS) in Israel, who said thataches and pains.
certain chemicals in snake venom may help treatFollowing this lead, Primor set his sights on the
arthritis – a condition that affects over 46 millionPalestinian viper – a common snake in Israel –
people in the United States alone.and extracted its venom. He found that the venom
“The scientific team that Primor heads at SIS hascontained about 1,000 molecules of which only four or
identified the chemicals in the snake venom of cobras,five are poisonous. He then isolated an analgesic
vipers and rattlers. The company is using thismolecule and made a synthetic copy called VeP-3.
knowledge to make a potent analgesic against chronic"About 99 percent of the venom is non-toxic, which
pain such as arthritis, and secondary pain caused byleaves us with a great source of possible drug
other diseases such as cancer. Primor suspects thatcomponents," said the 62-year-old snake specialist and
the venom has therapeutic properties also, but morebiochemist.
studies need to be done,” according to Britain IsraelWith this discovery, Primor hopes to create a snake
Communications and Research Center (BICOM).venom pain-reliving cream that will hit drugstores in the
As early as 2002, there have been reports of peoplenear future. He intends to use the same technique
who were mysteriously cured of arthritis after beingused by pharmaceutical company Merck & Company
bitten by snakes. Jose de Casa, 66, a longtime arthritisin mimicking the beneficial effects of the deadly venom
sufferer from Northamptonshire in England, waswithout its toxic effects.
cleaning his garden when an adder bit him. For the“Snake venom has already led to several new
next few months, he was pain-free.drugs used by Britons. Take for example, Aggrastat, a
“After the bite I noticed that the usual pain that I'super aspirin' introduced by Merck to prevent blood
have in the joint of my finger had gone completely andclots and to help prevent heart attacks in people
this lasted for three or four weeks. Then the pain washospitalized with severe chest pain. The drug came
reduced for a couple of months, although it is nowabout through the knowledge that some victims of
back to normal," he told the BBC News.snakebites bleed to death because the venom
Primor believes the bad publicity surrounding snakes iscontains proteins that prevent blood clotting,” said
unfair, considering that these creatures occupy anBICOM.
importance place in medicine. As far as he can“Researchers from Temple University in Philadelphia
remember, he has always been fond of snakes. Littleand Merck isolated molecules from actual viper venom,
did he know he would bring back his slithering friendsthen Merck built a synthetic molecule to mimic the
into the limelight again.viper's anti-clotting effect but without the toxins.
In 1986, his friend the late Professor Aharon Shulov ofThrough a similar process, SIS is attempting to create
the Hebrew University and Aviv Marx founded SISan arthritic pain reliever,” BICOM added.
that currently produces an antiserum for yellow