How Rheumatoid Arthritis is a Life Long Struggle

There is no shortage of rheumatoid arthritis treatments.salicylate (Trilasate®), diclofenac (Cataflam®,
A great many researchers are working on ways toVoltaren®, Arthrotec®), diflusinal (Dolobid®),
relieve the pain, disfigurement and discomfort of RA.etodolac (Lodine®), indomethicin (Indocin®),
But doctors say there is no cure! However, there isketoprofen (Orudis®, Oruvail®), meloxicam
hope.(Mobic®), nabumetone (Relafen®), oxaprozin
In recent years, researchers have developed a(Daypro®), piroxicam (Feldene®), sulindac
number of treatments that make life easier for the RA(Clinoril®) and tolementin (Tolectin®).
patient. The goal is to provide as normal a life asMany patients prefer naproxen sodium since it can be
possible for the sufferer with the lowest level oftaken once every 12 hours - rather than four times a
discomfort, disfigurement and interruption of a normalday as with some of the others.
life.NSAIDs provide quick but short-term help.
Until a cure is found, doctors find themselves minimizingDMARDs can take several weeks or months. Among
joint damage, disfigurement and pain while enhancingthose most commonly used are abatacept
the patient's ability to engage in enjoy a quality lifestyle.(Orencia®), adalimumab (Humira®), anakinra
Doctors have also learned that it's far easier for the(Kineret®), antimalarials, azathioprine (Imuran),
patient if families and loved ones understand what iscyclophosphamide cyclosporin A, d-penicillamine,
happening - that is, the nature of RA.etanercept (Enbrel®), gold salts, infliximab
So, what can actually be done? Three classes of(Remicade®), leflunomide (Arava®), methotrexate,
drugs are usually utilized for rheumatoid arthritisrituximab (Rituxan®) and sulfasalazine.
treatments:Most are very effective in preventing cartilage
1) non-steroidal anti-inflammatory agents (or NSAIDs),damage and the bone erosions that can come as
2) disease modifying anti-rheumatic drugs (orearly as during the first two years of the disease. As
DMARDs) and.a result, many doctors prescribe a DMARD as soon
3) corticosteroids.as RA is diagnosed.
The major benefit of NSAIDs is to relieve inflammation.But since DMARDs can be so slow acting, aspirin and
That decreases pain and improves function. However,other analgesics are also taken since they are so
NSAIDs alone can't change the course of the diseaseeffective in decreasing pain - but not in stopping the
nor prevent destruction of the affected joints.disease's progression.
For years, aspirin was the primary treatment - and stillSo, NSAIDs are taken to ease discomfort, particularly
relieves pain quite effectively. However, it oftenuntil DMARDs take effect.
causes stomach discomfort and has to be takenCorticosteroids are the third category of drugs used
repeatedly during the day. Thus, many doctors havewith RA. These are often prescribed for patients with
replaced it with other NSAIDs.severe cases who aren't responding to NSAIDs or
Fortunately, there are quite a few to choose from.DMARDs. However, there are side effects such as
Over-the-counter NSAIDs include naproxen sodiumweight gain, puffiness around the face, redness of the
(such as Aleve®) and ibuprofen (such as Advil®,cheeks, and even such oddities as the development of
Motrin® and Nuprin®.a "buffalo hump" over the neck.
Prescription NSAIDs include choline magnesium